itp, early presentation of thymoma
نویسندگان
چکیده
mediastinal neoplasms are uncommon tumors that can occur at any age but are most common through the fifth decades of life. a wide variety of systemic disorders are associated with 71% of thymomas. the symptoms of these as sociated disorders often lead to the original discovery of the mediastinal tumor. a 35-year-old female with petechia and purpura was admitted to sina hospital of the city of hamadan in 5/6/2000. the serum platelet count was 4000/microliter. after the primary evaluations idiopathic thrombocytopenic purpura (itp) was diagnosed and after corticosteroid therapy serum platelet count increased. after 2 month she was admitted to the neurology ward of our hospital with diagnosis of cerebro vascular accident (cva). in brain computed tomography (ct) scan a hyperdense lesion was reported that reveald hemorrhage in the temporoparietal region. the platelet count was 154000/microliter at this time which suggests the idea that some suppressive antibodies in the serum might lead to platelet disfunction. two years later she was admitted to shariati hospital with fatigue, left lid ptosis, speech disorder, bifacial weakness, diplopia and muscle force = 4/5. myasthenia gravis was diagnosed and in the chest ct scan a density associated with thymus was reported. thymectomy was performed for the patient and report of the pathologist was thymoma. after adjuvant radiotherapy serum platelet count increased and myasthenia gravis was improved and all of the patient's signs and symptoms resolved. itp must be considered as one of the paraneoplastic symptoms of thymoma.
منابع مشابه
effect of oral presentation on development of l2 learners grammar
this experimental study has been conducted to test the effect of oral presentation on the development of l2 learners grammar. but this oral presentation is not merely a deductive instruction of grammatical points, in this presentation two hypotheses of krashen (input and low filter hypotheses), stevicks viewpoints on grammar explanation and correction and widdowsons opinion on limited use of l1...
15 صفحه اولIntestinal pseudo-obstruction as initial presentation of thymoma.
A 45-year-old-man presented with severe vomiting, constipation, abdominal distention and bilateral ocular abductor palsy. Evaluation revealed diffuse autonomic dysfunction characterized by intestinal pseudo-obstruction, xerophthalmia, xerostomia, postural hypotension, erectile dysfunction and loss of sinus arrhythmia. Paraneoplastic work-up revealed thymoma. Most symptoms resolved after surgica...
متن کاملAcute presentation of thymoma with infarction or hemorrhage.
The presentation of thymomas is variable; most are asymptomatic and others present with local compression symptoms or a parathymic syndrome. Rarely thymomas present as an acute emergency with severe chest pain from either infarction or hemorrhage of the tumor. This rare presentation usually leads the clinician initially away from the diagnosis of thymoma. We present 4 patients who presented wit...
متن کاملPsychosis as an Early Presentation of Neuro-Brucellosis
Brucellosis is an endemic zoonotic infectious disease in Middle East countries including Iran. This infection may involve central nervous system. Psychosis has been reported in rare cases with chronic brucellosis.A 26-year-old male shepherd patient who developed neuro-brucellosis and psychosis is presented. He had hallucinations (visual and auditory) and delusions. He was also impulsive and had...
متن کاملIntrathoracic goiter and invasive thymoma: rare concomitant presentation.
We present a rare situation in which two mediastinal tumors of different topology and histology were found during the resection of an extensive mediastinal tumor in an asymptomatic patient. Different histologies within the same mass have been reported, although, to our knowledge, there have been no reports of different tumors at distinct locations. Thymomas and intrathoracic goiters account for...
متن کاملHypertrophic osteoarthropathy secondary to thymoma: rare presentation in childhood
Hypertrophic osteoarthropathy (HOA) is a group of syndromes characterized by clubbing, polyarthritis, and periosteal reaction. It is usually secondary to thoracic tumors and is extremely rare in children, therefore is easily to be misdiagnosed and delayed. In this study, we present an 11-year-old boy hospitalized because of joint swelling and pain accompanied by obvious clubbing, and was finall...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
international journal of hematology-oncology and stem cell researchجلد ۲، شماره ۱، صفحات ۴۵-۴۸
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023